ESTRO 2024 - Abstract Book

S2633

Clinical - Urology

ESTRO 2024

Figure 1. Distribution of number of lesions by imaging modality

Upon evaluation of the PSA levels at the time of imaging detection, it was observed that WB RM was performed with an average PSA of 1.62 and a median PSA of 1.06. In contrast, PET PSMA showed an average PSA of 1.72 and a median of 1.02. PET Cho had an average PSA of 3.61 and a median of 2.22, while traditional imaging methods documented an average PSA of 4.80 with a median of 1.31. A subsequent Kruskall-Wallis analysis revealed significant differences in the medians across these groups, evidenced by a p-value of less than 0.05 (as presented in Figure 2).

Fig. 2 - Distribution of PSA at first clinical recurrence by imaging

A deeper exploration into the data revealed shifts in the preferred imaging method for all MDTs throughout the study period. The analysis segmented treatments into three time intervals: those before 01/01/2015, those between 01/01/2015 and 01/01/2020, and those administered after 01/01/2020, as illustrated in Figure 3.

Fig. 3 - Count of imaging staging used before metastasis directed therapy (MDT)

Conclusion: