ESTRO 2024 - Abstract Book

S264

Brachytherapy - Gynaecology

ESTRO 2024

Rectal complications remain the main toxicity of modern brachytherapy, mainly proctitis and rectal bleeding. Efforts should be made to maintain rectal D2cc below 65 Gy. T-score, has showed clinical utility as prognostic factor especially in MDFS. T-score could predict parameters for IGABT such as volume and interstitial needle application. In our series we don´t found correlation between T-score>4 and 2-y G2-3 morbidity-free survival (rectal, urinary or sexual toxicity). Further studies are needed to evaluate the influence of different clinical factors on morbidity secondary to radiotherapy in patients with locally advanced cervical carcinoma.

Keywords: cervical cancer, morbidity, T-score

References:

1. Haie-Meder C, Potter R, van Limbergen E, Briot E, De Brabandere M, Dimopoulos J et al. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group() (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 2005; 74(3):235-245. 2. Pötter R, Haie-Meder C, Limbergen EV, Barillot I, Brabandere MD, Dimopoulos J et al. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 2006; 78(1):67-77. 3. Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, et al; EMBRACE Collaborative Group. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60. doi: 10.1016/j.ctro.2018.01.001. PMID: 29594251; PMCID: PMC5862686. EMBRACE study. 4. Vittrup AS, Kirchheiner K, Pötter R, Fokdal LU, Jensen NBK, Spampinato S, Haie-Meder C, Schmid MP, Sturdza AE, Mahantshetty U, Hoskin P, Segedin B, Bruheim K, Rai B, Wiebe E, van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Kirisits C, Lindegaard JC, Jürgenliemk-Schulz IM, Nout R, Tanderup K; EMBRACE Collaborative Group. Overall Severe Morbidity After Chemo-Radiation Therapy and Magnetic Resonance Imaging Guided Adaptive Brachytherapy in Locally Advanced Cervical Cancer: Results From the EMBRACE-I Study. Int J Radiat Oncol Biol Phys. 2023 Jul 15;116(4):807-824. doi: 10.1016/j.ijrobp.2023.01.002. Epub 2023 Jan 12. PMID: 36641039

2261

Digital Poster

2D and 3D planning in exclusive vaginal brachytherapy in postoperative endometrial cancer.

Clara Baltrons 1 , Faegheh Nooriankafshgari 1 , Antonio Herreros 1 , Irving Alexis Galindo 2 , Angeles Rovirosa 1

1 Hospital Clinic, radiotherapy, Barcelona, Spain. 2 Centro Oncologico estatal ISSEMYM, radiotherapy, chihuahua, Mexico

Purpose/Objective: