ESTRO 2024 - Abstract Book

S2936

Interdiscplinary - Other

ESTRO 2024

Table 1. Findings of toxicity according CTCAE classification in the 380 patients' reports. No toxicity grade 4 was detected.

Site

Grade 0

Grade 1

Grade 2

Grade 3

Skin

131 (34,5%)

189 (49,7%)

53 (14,0%)

7 (1,8%)

Mucosa

84 (22,1%)

174 (45,8%)

106 (27,9%)

16 (4,2%)

Conclusion:

This algorithm represents an example of the application of generative AI within radiation therapy, with the purpose of interpreting a text by providing from it structured data on the acute toxicity of radiation treatments. Certainly, this automated workflow represents a powerful tool that can speed up the reading of reports and their rapid use for data collection. However, some improvements are possible. Meanwhile, the accuracy of interpretation is still not perfect. This could either be due to errors in the text or incorrect interpretation by the AI. In addition, the need for training based on the analysis of human readers could be a possible interpretation bias. The next step will be to directly match the texts contained within the CTCAE publications with those within the folders, checking first for correct interpretation and then for application to novel cases. Generative AI is an extremely fertile field of modern information technology and will certainly enter more and more deeply into the daily activities of the radiation oncologist. The availability of well-designed applications will be a key starting point for increasingly widespread use.

Keywords: generative AI, toxicity detection

1879

Poster Discussion

MRI-guided cardiac radiotherapy using the 1.5T MR-linac: surveying emerging patterns of care

Osman Akdag 1 , Stefano Mandija 1 , Jacquelien Pomp 1 , Xinru Chen 2 , Jinzhong Yang 2 , Seungjong Oh 3 , Mark Trombetta 3 , Hendrick Tan 4 , Jeremy De Leon 5 , Michael Jameson 5,6,7 , Esma Efe 8 , Cem Önal 8,9 , Martin F Fast 1 1 University Medical Center Utrecht, Radiotherapy, Utrecht, Netherlands. 2 MD Anderson, Radiation Physics, Houston, USA. 3 Allegheny Health Network, Radiation Oncology, Pittsburgh, USA. 4 GenesisCare, Oncology, Perth, Australia. 5 Fiona Stanley Hospital, Radiation Oncology, Perth, Australia. 6 UNSW Sydney, Clinical Medicine, Sydney, Australia. 7 University of Wollongong, Medical and Radiation Physics, Wollongong, Australia. 8 Baskent University, Medicine, Ankara, Turkey. 9 Baskent University, Medicine, Adana, Turkey

Purpose/Objective:

The occurrence of cardiac tumors is relatively rare with sarcomas accounting for most primary malignancies[1]. The low prevalence of such pathology makes it difficult to standardize treatment protocols[2]. Cardiac tumors are generally removed surgically, often in combination with adjuvant chemotherapy for improved survival[3]. This highly invasive treatment is very complex and carries procedural risks. MRI-guided radiotherapy (MRgRT) is a non invasive treatment option offering direct target visibility that is rapidly emerging for patients with cardiac tumors