ESTRO 2024 - Abstract Book

S3042

Physics - Autosegmentation

ESTRO 2024

Figure 2 : Comparison of AI vs. Analytical methods for ten test cases, 17 vertebrae, for a total of 1020 landmark detections: statistically significant performance differences noted in T3, T4, T6, T8, T9, and T12 (p < 0.05).

Conclusion:

Two automated techniques for detecting vertebral landmarks in paediatric CT images were developed and assessed. The U-Net-based AI landmark detection method demonstrated superior accuracy compared to the analytical scripted image analysis approach. The study underscores the value of U-Net-based methodologies in advancing paediatric vertebrae growth measurements, addressing the challenges presented by the time-intensive nature of traditional manual methods. This work will facilitate the development of normal vertebral growth models from retrospective image data. Furthermore, it will enable the evaluation of post-radiotherapy growth impacts and improved dose response models for radiation-induced growth defects in paediatric radiation therapy patients.

Keywords: Pediatric, Vertebrae-growth, Landmarks

References:

[1] Hartley KA, Li C, Laningham FH, Krasin MJ, Xiong X, Merchant TE. Vertebral body growth after craniospinal irradiation. Int J Radiat Oncol Biol Phys. 2008;70:1343-9 doi:10.1016/j.ijrobp.2007.08.085.

[2] Sekuboyina A, Husseini ME, Bayat A, Löffler M, Liebl H, Li H, et al. VerSe: A Vertebrae labelling and segmentation benchmark for multi-detector CT images. Medical Image Analysis. 2021;73:102166 doi:https://doi.org/10.1016/j.media.2021.102166. [3] Jordan P, Adamson, P. M., Bhattbhatt, V., Beriwal, S., Shen, S., Radermecker, O., Bose, S., Strain, L. S., Offe, M., Fraley, D., Principi, S., Ye, D. H., Wang, A. S., Van Heteren, J., Vo, N.-J., & Schmidt, T. G. Pediatric Chest/Abdomen/Pelvic CT Exams with Expert Organ Contours (Pediatric-CT-SEG) (Version 2) [Data set]. In: Archive. TCI, editor.2021 https://doi.org/: https://doi.org/10.7937/TCIA.X0H0-1706.

[4] Jordan P, Adamson PM, Bhattbhatt V, Beriwal S, Shen S, Radermecker O, et al. Pediatric chest-abdomen-pelvis and abdomen-pelvis CT images with expert organ contours. 2022;49:3523-8 doi:https://doi.org/10.1002/mp.15485.

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Digital Poster

Cardiac substructure auto-contouring for ventricular tachycardia patients: a STOPSTORM.eu study

Luuk van der Pol 1 , Oliver Blanck 2 , Melanie Grehn 2 , Jakub Cvek 3 , Lukáš Knybel 3 , Brian Balgobind 4 , Joost Verhoeff 1,4 , Marcin Miszczyk 5 , Slawomir Blamek 6 , Sabrina Reichl 7 , Nicolaus Andratschke 7 , Bartłomiej Tomasik 6,8 , Martin Fast 1 1 University Medical Center Utrecht, Radiotherapy, Utrecht, Netherlands. 2 University Medical Center Schleswig Holstein, Radiation Oncology, Kiel, Germany. 3 University Hospital and Faculty of Medicine, Oncology, Ostrava, Czech Republic. 4 Amsterdam UMC location University of Amsterdam, Radiation Oncology, Amsterdam, Netherlands. 5 Maria