ESTRO 2024 - Abstract Book

S3292

Physics - Detectors, dose measurement and phantoms

ESTRO 2024

measurements, span from -0.41 to +0.41 mm and -0.52 to +0.03 mm, for the R90 and R50 respectively. The average range estimation has a statistical error of 0.07 mm (1σ) (see Figure 2). We also assessed the system sensitivity to changes in the number of protons (in terms of MU values), yielding satisfactory results for doses as low as 0.2 Gy.

Conclusion:

We are able to reconstruct dose maps from PET activation on-line, at clinically relevant dose levels and during the beam-on period, with an accuracy better than one millimeter, in the BP fall-off region. This validates the feasibility of the proposed experimental setup to be used for in-beam on-the-fly reconstruction of the 3D dose in a clinical scenario.

Keywords: real-time dose, in-beam PET, on-the-fly dose

References:

[1] Parodi, K., Paganetti, H., Shih, H. A., Michaud, S., Loeffler, J. S., DeLaney, T. F., ... & Bortfeld, T. (2007). Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy. International Journal of Radiation Oncology* Biology* Physics, 68(3), 920-934.