ESTRO 2024 - Abstract Book

S323

Brachytherapy - Head & neck, skin, eye

ESTRO 2024

Keywords: Scientometrics, collaboration, themes

References:

1. Ghazbani, A., Abdolahi, M., Mansourzadeh, M. J., et al. (2022). Knowledge domain and emerging trends in brachytherapy: A scientometric analysis. Precision Radiation Oncology, 6(3), 243-256

2. Tang, X., Zhao, Z., Zhao, H., et al. (2020). The 100 most cited articles in cervical cancer brachytherapy. Brachytherapy, 19(2), 181-193

3168

Digital Poster

Methods for Minimizing Side Effects in Nasal Vestibule Interventional Radiotherapy: An Update

Bruno Fionda 1 , Francesco Bussu 2,3 , Elisa Placidi 4 , Enrico Rosa 5 , Valentina Lancellotta 1 , Claudio Parilla 6 , Tiziano Zinicola 1 , Martina De Angeli 1 , Francesca Greco 4 , Mario Rigante 6 , Mariangela Massaccesi 1 , Maria Antonietta Gambacorta 1,7 , Luca Indovina 4 , Marco De Spirito 4,5 , Luca Tagliaferri 1 1 UOC Oncologic Radiotherapy, Diagnostic Imaging, Oncologic Radiotherapy and Hematology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy. 2 Divisione di Otorinolaringoiatria, Azienda Ospedaliero Universitaria, Sassari, Italy. 3 Dipartimento di Medicina, Chirurgia e Farmacia, Università di Sassari, Sassari, Italy. 4 UOC Physics for Life Sciences, Diagnostic Imaging, Oncologic Radiotherapy and Hematology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy. 5 Institute of Physics, Catholic University of Sacred Heart, Rome, Italy. 6 U.O.C. Otorinolaringoiatria, Dipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. 7 Institute of Radiology, Catholic University of Sacred Heart, Rome, Italy

Purpose/Objective:

Interventional radiotherapy, specifically brachytherapy, has emerged as the preferred therapeutic approach for managing early-stage nasal vestibule tumors due to its capacity to achieve high local control rates with minimal toxicity [1]. As an increasing number of patients opt for interventional radiotherapy as their primary treatment, there is a growing need to develop innovative strategies to minimize radiation exposure to critical organs, thereby reducing long-term side effects.

Material/Methods:

We investigated two distinct approaches to mitigate radiation exposure within the treatment area for 10 patients treated with interventional radiotherapy on the nasal vestibule. Firstly, we explored variations in the implantation technique, encompassing interstitial, endocavitary, or mixed approaches, with catheter placement following either the Paris system guidelines or an anatomical approach. Secondly, we scrutinized the dose distribution within the implant, with a particular focus on the dose non-uniformity ratio. In addition, we introduced two novel strategies (depicted in Figure 1) aimed at reducing radiation exposure to organs at risk: the use of metal shields to protect fixed organs like the eyes, and the implementation of a mouth swab to displace mobile organs, such as