ESTRO 2024 - Abstract Book

S3448

Physics - Dose calculation algorithms

ESTRO 2024

References:

[1] F. de Kermenguy et al., “Radio-induced lymphopenia in the era of anti-cancer immunotherapy,” in International Review of Cell and Molecular Biology, Academic Press, 2023. doi: 10.1016/bs.ircmb.2023.03.002.

[2] J. Shin et al., “HEDOS—a computational tool to assess radiation dose to circulating blood cells during external beam radiotherapy based on whole-body blood flow simulations,” Phys. Med. Biol., vol. 66, no. 16, p. 164001, Aug. 2021, doi: 10.1088/1361-6560/ac16ea.

[3] A. Hammi, H. Paganetti, and C. Grassberger, “4D blood flow model for dose calculation to circulating blood and lymphocytes,” Phys. Med. Biol., vol. 65, no. 5, p. 055008, Mar. 2020, doi: 10.1088/1361-6560/ab6c41.

[4] V. V. Ganusov and R. J. De Boer, “Do most lymphocytes in humans really reside in the gut?,” Trends Immunol., vol. 28, no. 12, pp. 514–518, Dec. 2007, doi: 10.1016/j.it.2007.08.009.

[5] V. V. Ganusov and J. Auerbach, “Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism,” PLOS Comput. Biol., vol. 10, no. 5, p. e1003586, mai 2014, doi: 10.1371/journal.pcbi.1003586.

[6] ICRP Publication 89, “Basic Anatomical and Physiological Data for Use in Radiological Protection Reference Values,” 2002, [Online]. Available: https://www.icrp.org/publication.asp?id=icrp%20publication%2089

[7] N. Bougas et al., “Surveillance after childhood cancer: are survivors with an increased risk for cardiomyopathy regularly followed-up?,” Br. J. Cancer, vol. 129, no. 8, Art. no. 8, Oct. 2023, doi: 10.1038/s41416-023-02400-0.

[8] H. Paganetti, “A review on lymphocyte radiosensitivity and its impact on radiotherapy,” Front. Oncol., vol. 13, 2023, Accessed: Aug. 31, 2023. [Online]. Available: https://www.frontiersin.org/articles/10.3389/fonc.2023.1201500

[9] W. Wick and M. Weller, “How Lymphotoxic Is Dose-Intensified Temozolomide? The Glioblastoma Experience,” J. Clin. Oncol., vol. 23, no. 18, pp. 4235–4236, Jun. 2005, doi: 10.1200/JCO.2004.00.8417.

[10] S. Ghosh et al., “Radiation-induced circulating myeloid-derived suppressor cells induce systemic lymphopenia after chemoradiotherapy in patients with glioblastoma,” Sci. Transl. Med., vol. 15, no. 680, p. eabn6758, Jan. 2023, doi: 10.1126/scitranslmed.abn6758.

[11] P. Chongsathidkiet et al., “Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors,” Nat. Med., vol. 24, no. 9, Art. no. 9, Sep. 2018, doi: 10.1038/s41591-018-0135-2.

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Dosimetric and clinical impact of non-linear 8-bit CT resampling to enhance synthetic-CT generation