ESTRO 2024 - Abstract Book

S3478

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2024

Conclusion:

This is the first study to introduce robust optimization for DYMBER plans where the margin concept is ill-defined. The relative photon/electron contribution is determined through simultaneous optimization for the two particle types and differs between PTV-based and robustly optimized plans. This implementation enables further investigation to determine the potential for OAR sparing improvement in the presence of uncertainties with robust optimization compared to the margin concept for DYMBER plans.

Supported by Varian, a Siemens Healthineers Company and SNSF grant 200021_185366. Dose calculations and optimizations were performed on UBELIX (wwww.id.unibe.ch/hpc), the high-performance cluster at the University of Bern.