ESTRO 2024 - Abstract Book

S347

Beachytherapy - Physics

ESTRO 2024

Conclusion:

We have successfully extended BRIGHT, a clinically introduced AI-based prostate HDR brachytherapy treatment plan optimization approach, to intuitively provide additional plans that are tailored towards explicit sparing of a specific OAR, whilst still including all aims of the clinical protocol. Evaluation with brachytherapy professionals showed that the resulting plans were very often correctly identified as being tailored toward additional sparing of a certain OAR.

Keywords: automated treatment planning, OAR sparing

References:

[1] D. Barten et al., “Artificial Intelligence based planning of HDR prostate brachytherapy: first clinical experience.,” Radiotherapy and Oncology, vol. 161, pp. S653–S655, Aug. 2021, doi: 10.1016/S0167-8140(21)07100 0. S. C. Maree et al., “Evaluation of bi-objective treatment planning for high-dose-rate prostate brachytherapy—A retrospective observer study,” Brachytherapy, vol. 18, no. 3, pp. 396–403, May 2019, doi: 10.1016/J.BRACHY.2018.12.010. [3] A. Bouter, N. H. Luong, C. Witteveen, T. Alderliesten, and P. A. N. Bosman, “The multi-objective real-valued gene-pool optimal mixing evolutionary algorithm,” in Proceedings of the Genetic and Evolutionary Computation Conference, New York, NY, USA: ACM, Jul. 2017, pp. 537–544. doi: 10.1145/3071178.3071274. [4] A. Bouter, T. Alderliesten, B. R. Pieters, A. Bel, Y. Niatsetski, and P. A. N. Bosman, “GPU-accelerated bi objective treatment planning for prostate high-dose-rate brachytherapy,” Med Phys, vol. 46, no. 9, pp. 3776–3787, 2019, doi: 10.1002/mp.13681. [2]

[5] M. J. Rivard et al., “Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations,” Med Phys, vol. 31, no. 3, pp. 633–674, Feb. 2004, doi: 10.1118/1.1646040.

1600

Digital Poster

Enhanced automated BT planning for cervical cancer – dwell time shaping using pseudo-structures

Frida Dohlmar 1,2 , Björn Morén 3 , Michael Sandborg 1,2 , Torbjörn Larsson 3 , Åsa Carlsson Tedgren 1,2,4

1 Linköping University, Medical Radiation Physics, Department of health, medicine and Caring Sciences, Linköping, Sweden. 2 Linköping University, Center for Medical Image Science and Visualization, Linköping, Sweden. 3 Linköping University, Department of Mathematics, Linköping, Sweden. 4 Karolinska University Hospital, Department of Medical Radiation Physics and Nuclear Medicine, Stockholm, Sweden

Purpose/Objective: