ESTRO 2024 - Abstract Book

S3547

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2024

Table 1. Comparison of target and OARs dosimetry for the CT vs sCT treatment plans for tumors site in the central, middle, and lateral area of the lung (group G C , G M , G L , respectively).

Conclusion:

The sCT generated by density assignment should be carefully used in the adaptive workflow for lung cancer treatments. The treatment plan calculated on the sCT when the target is located in the middle and lateral part of the lungs may lead to dosimetric inaccuracy.

Keywords: synthetic CT, lung cancer, plan adaptation

References:

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2. Prior P, Xinfeng Gore, Elizabeth Johnstone, CandiceLi, X. Allen. Technical Note: Is bulk electron density assignment appropriate for MRI-only based treatment planning for lung cancer? Medical Physics. 2017; 44 (7).

3. Schrenk O, Spindeldreier CK, Schmitt D, Roeder F, Bangert M, Burigo LN et al. The effect of density overrides on magnetic resonance-guided radiation therapy planning for lung cancer. Physics & Imaging in Radiation Oncology. 2018; 8: 23-27.

4. Benedict SH, Chairman A, Yenice KM, Followill D, Galvin JM, Hinson W et al. Stereotactic body radiation therapy: The report of AAPM Task Group 101." Med Phys 37(8):4078–4101. Available as AAPM. 2010.

5. Tang B, Liu M, Wang B, Diao P, Li J, Feng X et al. Improving the clinical workflow of a MR-Linac by dosimetric evaluation of synthetic CT. Front Oncol. 2022; 12: 920443.

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