ESTRO 2024 - Abstract Book

S3556

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2024

Conclusion:

The potential and feasibility of a GPU based full MC TPS implementation of IOeRT breast cancer treatments has been demonstrated. This long awaited tool will boost the treatment efficacy, overcoming the limits identified within the clinical trials carried out so far, and it will allow the first application of the FLASH effect into an IOeRT clinical workflow.

Keywords: IOeRT, ElectronFLASH, BreastCancer

References:

[1]C. Correa, et al, Accelerated partial breast irra- diation: Executive summary for the update of an astro evidence based consensus statement, Practical Radiation Oncology 7 (2) (2017) 73–79. doi:https://doi.org/10.1016/j.prro.2016.09.007.

[2] O. Kaidar-Person, at al, Apples and oranges: comparing partial breast irradiation techniques, Re- ports of Practical Oncology & Radiotherapy 25 (5) (2020) 780–782. doi:https://doi.org/10.1016/j.rpor.2020.07.008.

[3]F. Calvo, Intraoperative irradiation: Precision medicine for quality cancer control promotion, Radiation Oncology 12 (1), cited By 16 (2017) doi:10.1186/s13014-017-0764-5.

[4]F. A. Calvo, J. Serrano, M. Cambeiro, J. Aristu, J. M. Asencio, I. Ru- bio, J. M. Delgado, C. Ferrer, M. Desco, J. Pascau, Intra-operative electron radiation therapy: An update of the evidence collected in 40 years to search for models for electron-flash studies, Cancers 14 (15) (2022). doi:10.3390/cancers14153693. [5]U. Veronesi, et al, Intraoperative radiotherapy versus external radiotherapy for early breast cancer (eliot): a randomised controlled equivalence trial, The Lancet Oncology 14 (13) (2013) 1269–1277. doi:https://doi.org/10.1016/S1470- 2045(13)70497-2.

[6]G. Franciosini, et al. Gpu-accelerated monte carlo simulation of electron and photon interactions for radiotherapy applications, Physics in Medicine & Biology 68 (4) (2023) 044001. doi:10.1088/1361-6560/aca1f2.

1338

Poster Discussion

Treatment planning for MR-guided pancreas SBRT on a 1.5 T MR-Linac: a global consensus protocol

Guus Grimbergen 1 , Hidde Eijkelenkamp 1 , Louk M.W. Snoeren 1 , Uffe Bernchou 2,3 , Shawn Binda 4 , Christelle Bouchart 5 , Kerryn Brown 6 , Robert Chuter 7 , Paola Godoy Scripes 8 , William A. Hall 9 , Hanne D. Heerkens 10 , Jeremiah de Leon 11 , Robert Adam Mitchell 12 , Paul Renz 13 , Andrea Shessel 14 , Martijn P.W. Intven 1 , Gert J. Meijer 1 1 University Medical Center Utrecht, Department of Radiotherapy, Utrecht, Netherlands. 2 Odense University Hospital, Department of Oncology, Odense, Denmark. 3 University of Southern Denmark, Department of Clinical Research, Odense, Denmark. 4 Sunnybrook Health Sciences Centre, Department of Radiation Oncology, Toronto, Canada. 5 HUB Institut Jules Bordet, Department of Radiation Oncology, Brussels, Belgium. 6 Austin Health,