ESTRO 2024 - Abstract Book

S3801

Physics - Image acquisition and processing

ESTRO 2024

References:

[1] Stoiber et al. Radiot Oncol. 2012, 106(1), 96-100.

[2] Andratschke, N et al. Lancet, 2022 23, e469-e478.

[3] Neider, C et al. Int J Radiat Oncol Biol Phys, 2006, 66, (5), 1446-1449.

[4] Mayo, C et al. Int J Radiat Oncol Biol Phys, 2010, 76, (3), S36-S41.

766

Proffered Paper

Results of the ESTRO 2023 survey on the use of synthetic CT in MR-only radiotherapy

Marco Fusella 1 , Davide Cusumano 2 , Emilie Alvarez-Andres 3,4 , Riccardo Dal Bello 5 , Jennifer Dhont 6,7 , Cristina Garibaldi 8 , Fernanda Villegas 9,10 , Lorenzo Placidi 11 1 Abano Terme Hospital, Department of Radiation Oncology, Abano Terme (Padua), Italy. 2 Mater Olbia Hospital, Department of Medical Physics, Olbia (SS), Italy. 3 Faculty of Medicine and University Hospital Carl Gustav Carus of Technische Universität Dresden, 5Department of Radiotherapy and Radiation Oncology, Dresden, Germany. 4 Helmholtz-Zentrum Dresden-Rossendorf, 6OncoRay – National Center for Radiation Research in Oncology, Dresden, Germany. 5 University Hospital Zurich and University of Zurich, 4 Department of Radiation Oncology, Zurich, Switzerland. 6 Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B), Institut Jules Bordet, Department of Medical Physics, Brussels, Belgium. 7 Université Libre De Bruxelles (ULB), Radiophysics and MRI Physics Laboratory, Brussels, Belgium. 8 European Institute of Oncology IRCCS, Unit of Radiation Research, Milano, Italy. 9 Karolinska Institute, Department of Oncology-Pathology, Solna, Sweden. 10 Karolinska University Hospital, Radiotherapy Physics and Engineering, Medical Radiation Physics and Nuclear Medicine, Solna, Sweden. 11 Fondazione Policlinico Universitario Agostino Gemelli, Medical Physics Unit, Roma, Italy The emergence of synthetic CT (sCT) within MR-guided radiotherapy (MRgRT) represents a pivotal advancement in treatment planning, supporting MR-only workflows and online treatment adaptation. However, limited to no consensus guidelines exist regarding sCT development, implementation or clinical use, likely leading to heterogeneous practices across institutions. The use of sCT, either through an in-house developed algorithm or the use of commercial software, often involves a multidisciplinary team of medical physicists, engineers, developers and clinical end-users, highlighting the complexity of its application. In this study, we report the results of a survey that was created during the 2022 ESTRO Physics Working Group on “Next Generation MR-guided Radiotherapy: AI Applications for Planning and Image Guidance”, that aimed to define current practices in sCT development and clinical use, to guide future discussions on sCT standardization. Purpose/Objective: