ESTRO 2024 - Abstract Book

S3862

Physics - Image acquisition and processing

ESTRO 2024

Reproducible positioning of ROIs in homogeneous regions proved to be challenging, especially in the liver, and might therefore be an important contributor to the repeatability results [8]. Next steps are analyzing the complete dataset, investigating the effect of offline motion compensation [9], and including patient data. As tumor tissue typically exhibits higher signal compared to healthy tissue, repeatability might be better in tumors compared to current results. The results of this study are a first step in defining the best strategy for DWI acquisition for treatment-related changes in ADC of tumors in the abdomen on an MR-linac.

Keywords: MRI, Diffusion Weighted Imaging (DWI), MR-Linac

References:

[1] Van Houdt, P.J., et al. (2021). "Quantitative Magnetic Resonance Imaging for Biological Image-Guided Adaptive Radiotherapy." Frontiers in Oncology.

[2] Taouli, B., et al. (2009). "Diffusion ‐ weighted imaging of the liver: comparison of navigator triggered and breathhold acquisitions." Journal of Magnetic Resonance Imaging.

[3] Lovelock, D.M., et al. (2014). "The Effectiveness of a Pneumatic Compression Belt in Reducing Respiratory Motion of Abdominal Tumors in Patients Undergoing Stereotactic Body Radiotherapy." Technology in Cancer Research & Treatment.

[4] Swerkersson S., et al . (2018). "Optimizing diffusion-weighted magnetic resonance imaging for evaluation of lung tumors: A comparison of respiratory triggered and free breathing techniques." European Journal of Radiology Open.

[5] Szklaruk J., et al. (2019). "Comparison of free breathing and respiratory triggered diffusion-weighted imaging sequences for liver imaging." World Journal of Radiology.

[6] https://qibawiki.rsna.org/images/6/63/QIBA_DWI

[7] Shukla-Dave A., et al. (2019). "Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials." Journal of Magnetic Resonance Imaging.

[8] Bisgaard, A.L.H., et al. (2023). "Recommendations for improved reproducibility of ADC derivation on behalf of the Elekta MRI-linac consortium image analysis working group." Radiotherapy and Oncology.

[9] Pathak R., et al. (2019). "Considering tumour volume for motion corrected DWI of colorectal liver metastases increases sensitivity of ADC to detect treatment-induced changes." Scientific Reports.

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