ESTRO 2024 - Abstract Book

S4184

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

(0.33-0.55) 0.43 (0.13-1.32)

(0.12-0.15) 0.89 (0.27-1.39)

(0.41-0.66) 0.58 (0.28-1.16)

(0.54-0.83) 1.19 (0.56-2.06)

KIM vs Synchrony in patients

Conclusion:

KIM motion monitoring was implemented on a Radixact machine and used for independent validation of the Synchrony real-time prostate localization for MLC-tracking in phantoms and patients. The Synchrony system accurately detected the intrafractional motion of prostate tumors with sub-millimeter mean root-mean-square errors in all three directions and a mean 3D root-mean-square difference of 1.19 mm when compared to KIM in prostate cancer patients. The system adequately estimated the uncertainty of the position, which we deem acceptable for clinical use, and could therefore potentially be used to reduce target margins during treatment without compromising patient safety or confidence in delivered dose.

Keywords: MLC-tracking, adaptive, Synchrony

References:

1: Keall P.J. et al., AAPM Task Group 264: The safe clinical implementation of MLC tracking in radiotherapy. Medical Physics, 2020. 48(5):pp e44-e64.

2: Ballhausen, H., Li M. and Belka C., The ProMotion LMU dataset, prostate intra-fraction motion recorded by transperineal ultrasound. Scientific Data, 2019. 6(1): p. 269.

3: Poulsen P.R., Cho B. and Keall P.J., A method to estimate mean position, motion magnitude, motion correlation, and trajectory of a tumor from cone-beam CT projections for image-guided radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 2008. 72(5): pp. 1587-96.

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Digital Poster

Pre-treatment QA for online-adaptive PT: Status-quo workflow assessment and sanity check development

Lukas C Wolter 1,2 , Kenneth Poels 3 , Fabian Hennings 1,2 , Kevin Souris 4 , Theresa Lenk 5 , Kristin Stützer 1,2 , Christian Richter 1,2,5 1 OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany. 2 Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiooncology - OncoRay, Dresden, Germany. 3 Department of Radiotherapy Oncology, University Hospitals Leuven, Leuven, Belgium. 4 Ion Beam Applications SA, IBA, Louvain-la Neuve, Belgium. 5 Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany