ESTRO 2024 - Abstract Book

S4231

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

patients and the need for ongoing improvements of IGRT technologies. This achievement paves the way for broader adoption of the KIM technology for motion management in radiation therapy.

Keywords: Real-time IGRT in liver SABR, 6DoF liver motion

References:

[1] Anastasi G, Bertholet J, Poulsen P, Roggen T, Garibaldi C, Tilly N et al.. Patterns of practice for adaptive and real time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management. Radiother Oncol. 2020; 153: 79-8.

[2] Mackonis ERC, Hardcastle N, Haworth A. Stereotactic ablative body radiation therapy (SABR) in NSW. Physical and Engineering Sciences in Medicine. 2020; 43(2): 641-650.

[3] Worm ES, Hoyer M, Hansen R, et al. A prospective cohort study of gated stereotactic liver radiation therapy using continuous internal electromagnetic motion monitoring. Int J Radiat Oncol Biol Phys. 2018; 101: 366–375.

[4] Kilby W, Dooley JR, Kuduvalli G, Sayeh S, Maurer CR. The CyberKnife® Robotic Radiosurgery System in 2010. Technology in Cancer Research & Treatment. 2010; 9(5): 433-452. doi:10.1177/153303461000900502.

[5] Tallet A, Boher JM, Tyran M et al. Is MRI-Linac helpful in SABR treatments for liver cancer? Front Oncol. 2023; 13: 1130490. doi: 10.3389/fonc.2023.1130490. PMID: 37007109; PMCID: PMC10061121.

[6] Poulsen PR, Cho B, Langen K, Kupelian P, Keall PJ. Three dimensional prostate position estimation with a single x ray imager utilizing the spatial probability density. Phys Med Biol. 2008; 53: 4331.

[7] Keall PJ, Nguyen DT, O’Brien R et al..Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy: Results From the TROG 15.01 SPARK Trial. Int J Radiat Oncol Biol Phys. 2020; 107(3):530-538. doi:10.1016/j.ijrobp.2020.03.014.

[8] Lee D, Nguyen D, Moodie T et al.. Study protocol of the LARK (TROG 17.03) clinical trial: a phase II trial investigating the dosimetric impact of Liver Ablative Radiotherapy using Kilovoltage intrafraction monitoring. BMC Cancer. 2021; 21: 494. doi.org/10.1186/s12885-021-08184.

[9] 6DoF Robotic Motion Phantom. github.com/ACRF-Image-X-Institute/6-DoF-Robotic-Motion-Phantom; [accessed 6 February 2021].

[10] Wong JW, Sharpe MB, Jaffray DA, et al.. The use of active breathing control (ABC) to reduce margin for breathing motion. Int J Radiat Oncol Biol Phys. 1999; 44: 911–919.

[11] Kubo, H.D., Len, P.M., Minohara, S.-i. and Mostafavi, H. Breathing-synchronized radiotherapy program at the University of California Davis Cancer center. Med Phys. 2000, 27: 346-353.

[12] Poulsen, P.R., Schmidt, M.L., Keall, P., Worm, E.S., Fledelius, W. and Hoffmann, L. A method of dose reconstruction for moving targets compatible with dynamic treatments. Med Phys. 2012; 39: 6237-6246. doi.org/10.1118/1.4754297.

[13] Motion-included dose Reconstruction on Pinnacle TPS. github.com/ACRF-Image-X-Institute/Motion-Included Dose-Recon-on-Pinnacle-TPS; [accessed 10 February 2022].