ESTRO 2024 - Abstract Book

S4236

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

In conclusion, our findings show the potential of the MLC-tracking for real-time tracking of prostate and lung motion in radiotherapy. The system adeptly tracked both types of motion, enhancing both dosimetric and geometric precision relative to static plans. The biggest challenges for clinical introduction were establishing tolerances for beam holds during treatment, and there may be room for improvements. The system's clinical incorporation attests to its practicality, and the presented dose simulations suggests an improved dose target coverage with tracking. To further establish the introduction and assess the benefits and limitations of the MLC tracking technique, we have introduced a prospective clinical trial that are currently enrolling patients, with the goal to reduce margins for the treated cancer types (NCT05844761).

Keywords: MLC-tracking, tomotherapy, adaptive

References:

1. Keall, P.J., et al., The management of respiratory motion in radiation oncology report of AAPM Task Group 76. Med Phys, 2006. 33(10): p. 3874-900.

2. Ballhausen, H., M. Li, and C. Belka, The ProMotion LMU dataset, prostate intra-fraction motion recorded by transperineal ultrasound. Scientific Data, 2019. 6(1): p. 269.