ESTRO 2024 - Abstract Book

S4335

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

With single arc 10 MV FFF, very slightly significant increments were found in the dose objectives of the bladder (~1%). No statistical differences were found both in plan quality and complexity between the three arrangements. Moreover, we did not see any correlation between the two quantities, e.g. patient P1 with the highest MUs achieved PQIs below the mean values. Focusing on single patients, plan quality was mainly correlated with patient anatomy.

Preliminary results of the PSQA confirmed the same degree of delivery accuracy for the three arrangements. The BOTs were around 3.5 min for double arcs and 2 min for single arcs, with a significant reduction of about 1.5 min.

Conclusion:

The high quality, fast and accurate dose delivery of single arcs indicated the feasibility of this geometry for low- and intermediate-risk prostate SBRT. In particular, the significant reduction of the delivery time in comparison to double arc arrangement improve treatment robustness against intra-fraction prostate motion and so patient safety.

Keywords: VMAT, SBRT, prostate

References:

V. J. Brand, M. T. W. Milder, M. E. M. C. Christianen, M. S. Hoogeman, and L. Incrocci, “Seminal vesicle inter- and intra fraction motion during radiotherapy for prostate cancer: A review,” Radiotherapy and Oncology, vol. 169, pp. 15–24, Apr. 2022, doi: 10.1016/j.radonc.2022.02.002.