ESTRO 2024 - Abstract Book

S4342

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

Figure 1. A categorical scatter plot of the organ at risk mean doses of the clinical pre-treatment plan, the accumulated adaptive Monaco doses, and the accumulated doses of the adaptive plans optimized in RayStation.

Conclusion:

The dose accumulation pipeline can be used to quantify dosimetric differences between the online adaptive treatment plans and the pre-treatment plan of prostate cancer patients treated on a 1.5 T MR-linac. The novel pre treatment and adaptive optimization approach results in prostate IMRT plans with lower mean OAR dose as compared to the clinical plans.

Keywords: Dose accumulation, online adaptive, MR-guided.

References:

1. McDonald BA, Zachiu C, Christodouleas J, Naser MA, Ruschin M, Sonke JJ, et al. Dose accumulation for MR guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation. Front Oncol 2023;12(January):1–14.

2. Winkel D, Bol GH, Kroon PS, van Asselen B, Hackett SS, Werensteijn-Honingh AM, et al. Adaptive radiotherapy: The Elekta Unity MR-linac concept. Clin Transl Radiat Oncol 2019;18:54–9.

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