ESTRO 2024 - Abstract Book

S451

Clinical - Breast

ESTRO 2024

status

>70

88

43(83)

45(88)

0.58

Neurologic function

<2

83

41(79)

42(78)

0.80

Keywords: Brain metastases, WBRT, SRS, SRT

References:

Ankita G, Yadav BS, Ballari N, et al. LINAC-based stereotactic radiosurgery/radiotherapy for brain metastases in patients with breast cancer. Journal of Radiotherapy in Practice , Volume 21 , Issue 3 , September 2022 , pp. 351 – 359

192

Digital Poster

Estimated radiobiological parameters for breast hypofractionated schemes if raw data is unavailable

Pau Guardiola-Zaragoza 1 , Damián Guirado 2 , Marcelino Hermida-López 1

1 Hospital Universitari Vall d'Hebrón, Servei de Física i Protecció Radiològica, Barcelona, Spain. 2 Instituto de Investigación Biosanitaria (ibs. GRANADA), San Cecilio Clinical University Hospital, Unidad de Radiofísica, Granada, Spain

Purpose/Objective:

Hypofractionated radiotherapy schemes for breast cancer gained relevance in the last years, becoming a common treatment option. Certain radiobiological parameters describe the tumor response to radiotherapy, and allow comparing different schemes. These parameters are not always accessible, as some studies do not provide them, neither the raw data. We propose a Monte Carlo-based method adapted from the work by Guirado et al. [1] to estimate radiobiological parameters using only the data provided by the studies in terms of tumor control probability (TCP), without accessing to the raw data.

Material/Methods: