ESTRO 2024 - Abstract Book

S4648

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTR0 2024

Fig. 1. Experimental setup showing the head phantom between the PET scanner panels. B) A CT image of the head phantom is imported into a custom-modified research version of the RayStation treatment planning system. C) GATE simulation setup based on the experimental setup.

Results:

The calculated 12N and long-lived positron emitter activity induced in the head phantom for the spot irradiation show good agreement with results based on the framework. The 12N production range values were 95.30±0.19 mm and 97.25±0.30 mm for measurement and simulation, respectively, and the production ranges for long-lived isotopes were 89.85±0.01 mm and 90.85±0.1 mm for measurement and simulation, respectively. A similar analysis was done for measurement using the treatment beam, and the production range for the sum of all isotopes was 102.81±0.03 mm and 102.15±0.06 mm for measurement and simulation, respectively. The relative difference between FWHM values for lateral profiles is less than 1%. For the range measurement, 2D reconstructed images and both longitudinal and lateral activity profiles are shown in Fig. 2. The 38K and 38Ca radioisotopes, which are not taken into account in the simulation, represent the main difference between experimental and simulation profiles in the bone-filled entrance of the head phantom (at Y-values around 60 mm).