ESTRO 2024 - Abstract Book

S4659

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTR0 2024

Conclusion:

In this study, the prototype optimization algorithm RapidScan, which incorporates minimum MU objectives into optimization and allows for adjustments to layer-spacing, was tested for DIBH liver IMPT. Plans optimized using this algorithm reduced field delivery times by half. This reduction would lead to faster treatment times and less breath holds for patients, reducing the burden to the patient and increasing treatment reproducibility. With near equivalent dosimetric quality and plan deliverability, RapidScan demonstrates the potential for these shorter treatments without compromising plan fidelity. Further investigation of other combinations of minimum MUs and energy-layers may reduce field delivery times even greater and additional optimizations could also decrease the minor dosimetric variations in plans. Application to additional treatment sites is also warranted.

Keywords: Proton Optimization, Motion Managment Efficiency

1883

Proffered Paper

Benefits and limitations of LET d optimization for carbon ion radiotherapy in sacral chordomas

Giovanni Parrella 1 , Silvia Molinelli 2 , Giuseppe Magro 2 , Agnieszka Chalaszczyk 3 , Maria Rosaria Fiore 3 , Mario Ciocca 2 , Lars Glimelius 4 , Chiara Paganelli 1 , Ester Orlandi 5 , Guido Baroni 1 1 Politecnico di Milano, Department of electronic, information and bioengineering, Milano, Italy. 2 Centro nazionale di adroterapia oncologica, CNAO, Medical physics unit, Pavia, Italy. 3 Centro nazionale di adroterapia oncologica, CNAO, Radiotherapy unit, Pavia, Italy. 4 Raysearch Laboratories, Physics group, Stockholm, Sweden. 5 Centro nazionale di adroterapia oncologica, Clinical unit, Pavia, Italy