ESTRO 2024 - Abstract Book

S4721

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTR0 2024

Keywords: proton therapy, adaptive pt, robust planning, lung

References:

[1 Liu W, Zhang X, Li Y, Mohan R. Robust optimization of intensity modulated proton therapy. Medical Physics 2012;39:1079–91. https://doi.org/10.1118/1.3679340.

[2] Pflugfelder D, Wilkens JJ, Oelfke U. Worst case optimization: A method to account for uncertainties in the optimization of intensity modulated proton therapy. Physics in Medicine and Biology 2008;53:1689–700. https://doi.org/10.1088/0031-9155/53/6/013.

[3] Fredriksson A, Forsgren A, Hårdemark B. Minimax optimization for handling range and setup uncertainties in proton therapy. Medical Physics 2011;38:1672–84. https://doi.org/10.1118/1.3556559.

[4] Unkelbach J, Paganetti H. Robust Proton Treatment Planning: Physical and Biological Optimization. Seminars in Radiation Oncology 2018;28:88–96. https://doi.org/10.1016/j.semradonc.2017.11.005.

[5] Szeto YZ, Witte MG, van Kranen SR, Sonke JJ, Belderbos J, van Herk M. Effects of anatomical changes on pencil beam scanning proton plans in locally advanced NSCLC patients. Radiotherapy and Oncology 2016;120:286–92. https://doi.org/10.1016/j.radonc.2016.04.002.

2927

Digital Poster

Cardiac radioablation for ventricular tachycardia: photons versus protons dosimetric comparison

Eleonora Rossi 1 , Alfredo Mirandola 1 , Luca Maria Colombo Gomez 2 , Laura Mantovani 2 , Luca Trombetta 1 , Elisabetta Bonzano 3 , Adele Valentini 4 , Nicoletta Basla 4 , Viviana Vitolo 1 , Amelia Barcellini 1,5 , Andrea Pella 1 , Roberto Rordorf 6 , Riccardo Di Liberto 2 , Ester Orlandi 1 , Mario Ciocca 1 1 Centro Nazionale di Adroterapia Oncologica, Clinical Department, Pavia, Italy. 2 IRCCS Fondazione Policlinico San Matteo Foundation, Medical Physics Department, Pavia, Italy. 3 IRCCS Fondazione Policlinico San Matteo Foundation, Department of Radiotherapy, Pavia, Italy. 4 IRCCS Fondazione Policlinico San Matteo Foundation, Radiology Department, Pavia, Italy. 5 University of Pavia, Internal Medicine and Medical Therapy Department, Pavia, Italy. 6 IRCCS Fondazione Policlinico San Matteo Foundation, Arrhythmia and Electrophysiology, Cardiac Intensive Care Unit, Pavia, Italy

Purpose/Objective:

Ventricular tachycardia is a major public health problem and may cause sudden cardiac death. StereoTactic Arrhythmia Radioablation (STAR) is an emerging and not invasive approach, based on the delivery of a high dose (25 Gy) of radiation in a single fraction. This in-silico study aimed to assess the feasibility of STAR for both photons and