ESTRO 2024 - Abstract Book

S4950

Physics - Quality assurance and auditing

ESTRO 2024

Conclusion:

This study found that a biological basis for the clinical trial credentialing criteria was not only reasonable but also revealed a slightly different set of failing results as compared to the current dosimetric criteria. As such, a biologically based criteria may be a more wholistic and clinically relevant means of assessing the acceptability of credentialing phantom results.

Keywords: Clinical trial, credentialing, dosimetry,

References:

[1] Li, Allen et al. “The use and QA of biologically related models for treatment planning: short report of the TG-166 of the therapy physics committee of the AAPM.” Med Physics 39 3 (2012): 1386-409 .

[2] Nahum AE, Uzan J. (Radio)biological optimization of external-beam radiotherapy. Comput Math Methods Med. 2012;2012:329214

[3] Nutting CM, Morden JP at al; PARSPORT trial management group. Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncol. 2011 Feb;12(2):127-36.

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