ESTRO 2024 - Abstract Book

S5045

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2024

AUC

Accuracy

Sensitivity

Specificity

Train

Test

H’ V5

0.696 ± 0.023

0.602 ± 0.070

0.595 ± 0.044

0.742 ± 0.027

0.327 ± 0.053

H’ V20

0.694 ± 0.029

0.524 ± 0.041

0.607 ± 0.018

0.718 ± 0.019

0.237 ± 0.068

H’ V30

0.736 ± 0.015

0.668 ± 0.057

0.708 ± 0.040

0.798 ± 0.030

0.493 ± 0.072

H’ MLD

0.736 ± 0.026

0.724 ± 0.042

0.729 ± 0.035

0.821 ± 0.013

0.541 ± 0.061

Radiomics

0.737 ± 0.020

0.633 ± 0.036

0.675 ± 0.031

0.770 ± 0.013

0.513 ± 0.125

Conclusion:

We evaluated the prediction performance of RP using homodogy-based features. Our results showed better predictive performance than the conventional radiomics method. This shows that homodogy-based analysis using machine learning is a promising tool for modelling RP prediction. Based on the result, there is a potential for improvement in prediction accuracy by overcoming the class imbalance problem.

Keywords: Homology, modelling

References:

1) Rodrigues, G., Lock, M., D’Souza, D., Yu, E. and Van Dyk, J. Prediction of radiation pneumonitis by dose–volume histogram parameters in lung cancer—a systematic review. Radiotherapy and Oncology, 71(2), pp.127–138, 2004

1424

Digital Poster

Multimodality radiomics boosts precise online risk stratification in prostate cancer radiotherapy

Wanrong Yang 1,2,3 , Xuhao Dong 1 , Zhihui Wang 1 , Hao Cao 1 , Zican Li 1 , Qinyao Sun 4 , Haifeng Wang 1 , Yanjie Zhu 1 , Dong Liang 1 , Yihang Zhou 1,5 1 Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Department of Biomedical and Health Engineering, Shenzhen, China. 2 University of Liverpool, EPSRC Centre for Doctoral Training in Distributed Algorithms, Liverpool, United Kingdom. 3 University of Liverpool, Department of Computer Science, Liverpool, United Kingdom. 4 University of Electronic Science and Technology of China, Department of Biomedical Engineering, Chengdu, China. 5 Hong Kong Sanatorium & Hospital, Medical Physics and Research Department, Hong Kong, China