ESTRO 2024 - Abstract Book

S5076

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2024

Conclusion:

The first NTCP models for late rectal bleeding that apply to multiple fractionation schedules were generated. Only BED was used to account for differences in fractionation schedules; the applied schedule was not one of the predictors. An EUD (n=0.1) – based model performed best based on calibration and discriminative ability.

Keywords: prostate, hypofractionation

References:

1. Fowler, J. F. (2005). The radiobiology of prostate cancer including new aspects of fractionated radiotherapy. Acta Oncologica, 44(3), 265-276.

2. Fiorino, C., Valdagni, R., Rancati, T., & Sanguineti, G. (2009). Dose–volume effects for normal tissues in external radiotherapy: Pelvis. Radiotherapy and Oncology, 93(2), 153-167.

3. Mazeron, R., Fokdal, L. U., Kirchheiner, K., Georg, P., Jastaniyah, N., Šegedin, B., Mahantshetty, U., Hoskin, P., Jürgenliemk-Schulz, I., Kirisits, C., Lindegaard, J.C., Dörr, W., Haie-Meder, C., Tanderup, K., & Pötter, R. on behalf of the EMBRACE collaborative group. (2016). Dose–volume effect relationships for late rectal morbidity in patients treated

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