ESTRO 2024 - Abstract Book

S1409

Clinical - Head & neck

ESTRO 2024

Figure 1: Histogram of Baseline log2 cfDNA titres.

Correlation statistics and p-values for tumour volumes and log2 HPV cfDNA are presented in Table 2.

Tumour volume

Spearmans ρ

p value

GTVp

0.254

0.027

GTVn

0.327

0.004

GTVt

0.391

<0.001

Table 2: Correlation statistics between tumour volume and Baseline log2 cfDNA

These show weak, but statistically significant associations between baseline log2 HPV cfDNA copy number, and disease volume for all GTV volumes, with the strongest correlation for total disease volume (GTVt). A scatter plot with linear best fit model is presented in Figure 2.