ESTRO 2024 - Abstract Book

S1419

Clinical - Head & neck

ESTRO 2024

N Stage

Absent

Reference

1.700 (0.480 – 4.945);

p =

Present

0.662

Concurrent Chemotherapy

Given

Reference

2.092 (0.663 – 4.880);

p =

Not given

0.288

Interval between two RT

≤2 yrs

Reference

0.481 (0.198 – 2.012);

p =

>2 yrs

0.071

Re-RT dose

> 60 Gy

Reference

Reference

2.003 (1.332 – 6.880);

p =

2.901 (1.228 – 5.098); p = 0.032 1.118 (1.021 – 1.212); p = 0.039

≤ 60 Gy

0.029

Tumour volume

Continuous

1.109 (1.010 – 1.093); p = 0.018

Conclusion:

Tumour volume in 3-dimensions is a poor prognostic factor for early tumour response for patients with recurrent HPV negative oropharyngeal cancer undergoing radical Re-RT. Further research should be done in this direction so as to consider incorporated of tumour volume into staging system and prognostication of recurrent head and neck cancer.

Keywords: tumour volume, oropharyngeal cancer, reirradiation

2675

Poster Discussion

Automated analysis of elective neck treatment in patients with oropharyngeal squamous cell carcinoma

Andrew Hope 1,2 , Joseph Marsilla 3 , Joshua Siraj 3 , Jun Won Kim 4 , Sejin Kim 2,3 , Mattea Welch 5 , Shao Hui Huang 1,2 , Brian O'Sullivan 2 , Scott Bratman 1,2 , Benjamin Haibe-Kains 3,5 1 University of Toronto, Radiation Oncology, Toronto, Canada. 2 Princess Margaret Cancer Centre, Radiation Medicine, Toronto, Canada. 3 University of Toronto, Medical Biophysics, Toronto, Canada. 4 Gangnam Severance Hospital, Yonsei University College of Medicine, Radiation Oncology, Seoul, Korea, Republic of. 5 Princess Margaret Cancer Centre, Cancer Digital Intelligence, Toronto, Canada

Purpose/Objective: