ESTRO 2024 - Abstract Book

S2249

Clinical - Upper GI

ESTRO 2024

Figure 2: ROC curves of ERImid alone (left) and in combination with Vpre (right) in discriminating complete responding patients

Conclusion:

Despite the limited numbers, interim analysis of the ESCAPE study suggests ERI as a robust predictor of complete response after nCRT for esophageal cancer. In particular, ERImid alone seems to capture most of the picture giving the possibility of early predicting complete response. This is highly promising for a faster incorporation in clinical practice and translation toward more personalized treatment protocols, even due to the intrinsic generalizability of an index based just on MRI-based volume regression patterns. Further validation on larger populations is warranted.

Keywords: Esophageal cancer, Volume Regression, MR imaging

References:

References: 1) Fiorino C et al. Radiother Oncol. 2018;128:564 – 568; 2) Broggi S et al. Radiother Oncol. 2020;149:174 180.3) Cusumano D et al. Radiother Oncol. 2022;174:30-36.

Acknowledgement: The study was supported by AIRC (Italian Association for Cancer Research) IG 2019 - ID. 23015 project

2395

Digital Poster

Local control and toxicity after upper abdominal SBRT with Simultaneous Integrated Protection (SIP)

Gianluca Radicioni 1,2 , Simon K B Spohn 1,2,3 , Alexandra Eichhorst 1,2 , Alexander Rühle 1,2 , Nanna Hartong 1,2 , Ilinca Popp 1,2 , Sonja Adebahr 1,2 , Thomas B Brunner 4 , Anca-Ligia Grosu 1,2 , Eleni Gkika 1,2