ESTRO 2024 - Abstract Book

S2792

Interdisciplinary - Health economics & health services research

ESTRO 2024

builds the base of the first phase of this study. We screened systematically for published papers which serve as a base for the development of safety indicators.

Material/Methods:

A systematic review in the PubMed database was conducted using two combinations of keywords, with focus on radiation oncology and safety on the one hand, and the combination of either systemic tumor therapy, medication, or supportive therapy in combination with safety on the other hand (table 1). All publications were independently screened by abstract by one radiation oncologist and one medical physicist. Papers were excluded if the full texts were not available in English or German, if they deal with special techniques not available throughout most institutions (e.g., proton therapy), if they only consider country-specific aspects not applicable for Germany, or if they only consider preclinical data. Debatable abstracts were discussed and selected or dismissed. Possible safety indicators were extracted in the full text-screening from all manuscripts. Search #1 keywords, title or abstract "quality indicator*" OR "safety indicator*" OR "safety assessment" OR "safety barrier" OR "performance indicator*" OR "patient safety" OR "risk assessment" OR "quality assurance" OR "safety measure*" OR "safety climate" OR "safety culture" OR "patient safety" [MeSH Terms] OR "Quality Indicators" OR "Health Care" [MeSH Terms] Combined (AND) either with search #2a or search #2b Search #2a keywords, title or abstract Search #2b keywords, title or abstract "oncology" OR "radiation oncology" OR "radiotherapy" OR "radiation therapy" OR "Radiotherapy" [MeSH Terms] Table 1: Search strategy in this study.

"medication safety" OR "chemotherapy safety" OR "medication error*" OR "drug monitoring" OR "drug interaction*" OR "medication reconciliation„ OR "drug administration" OR "oncology pharmacy" OR "systemic therapy" OR "nutrition" OR "pain therapy" OR "analgesic*"OR "psychooncology" OR "distress" OR "psycho-oncology" OR "toxicity management" OR "antiemetic" OR "distress" OR "anxiety" OR "depression"OR "nausea" OR "pain" OR "psychosocial"

Results:

The PubMed search offered 6.265 references, of which 5.916 were excluded in the abstract screening. Of 249 included abstracts, 28 % offered guidelines or expert opinions, 21 % defined indicators for quality or safety, 31 % described measures to improve safety and 20 % underlines certain risks in radiation oncology and supportive care, or medication safety or safety of systemic cancer therapy. 120 papers were included after the full text-screening and based on those, 320 safety indicators were identified. Of those, 4 % describe human resources, education, or talent management, 19 % describe institutional culture aspects, 26 % describe risk- and quality management patterns, 28 % describe aspects of the subprocesses through the therapeutic process, 9 % describe application of systemic therapies, and 13 % describe aspects of supportive care and medication safety.

Conclusion: