ESTRO 2024 - Abstract Book

S1487

Clinical - Lower GI

ESTRO 2024

group compared to 43% in no boost group. LPLND was done in 38 % of patients in the boost vs 34% in no boost group. Positive LPLN at the end of treatment was seen in 31 % of cases vs 53 % of cases of boost and no boost group respectively. For patients in whom LPLND was not done; nodal response was observed. It was seen to be 91 % in the boost vs 75 % in no boost group. The strength of our study is the propensity score matching accounting for the effect of confounding factors. There was uniformity in the radiotherapy treatment course as all patients have received a long course radiotherapy.

Conclusion:

Giving a boost to positive LPLN along with the standard practice of neoadjuvant treatment and surgery or wait and watch approach is safe and can result in better survival outcomes and improved locoregional control.

Keywords: Rectum, LPLN, Boost

References:

1. Akiyoshi T, Matsueda K, Hiratsuka M, Unno T, Nagata J, Nagasaki T, et al. Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer. Ann Surg Oncol. 2015;22:614–20.