ESTRO 2024 - Abstract Book

S5704

RTT - Patient experience and quality of life

ESTRO 2024

Administration of glutamine during RT±QT treatment in HNC patients could reduce the duration and severity of mucositis. These results may reduce the use of opioids, improve treatment adherence and the quality of life of our patients, although future studies are needed.

Keywords: Mucositis

References:

Pytlik R, Benes P, Patorkova M, Chocenska E, Gregora E, Prochazka B, et al. Standardized parenteral alanyl glutamine dipeptide supplementation is not beneficial in autologous transplant patients: A randomized, double blind, placebo controlled study. Bone Marrow Transplant 2002;30(12):953-961. Piccirillo N, De Matteis S, Laurenti L, Chiusolo P, Sora F, Pittiruti M, et al. Glutamine-enriched parenteral nutrition after autologous peripheral blood stem cell transplantation: Effects on immune reconstitution and mucositis. Haematologica. 2003;88(2):192-200

Savarese DM, Savy G, Vahdat L, Wischmeyer PE, Corey B. Prevention of chemotherapy and radiation toxicity with glutamine. Cancer Treat Rev. 2003;29(6):501-513

Avila A, Cardona AF, Perea AH. Fisiopatología, prevención y tratamiento de la mucositis inducida por quimio y radioterapia. Rev Col Cancerol. 2000;41(1):36-53.

2408

Digital Poster

Radiographer led feasibility trial of remote cardiac monitoring post radical thoracic radiotherapy

Phil Fendall Amaro 1 , Alan McWilliam 2,3 , Lee Whiteside 1 , Louise McHugh 1 , Rachael Bailey 1 , Jacqui Bridge 1 , Lucy Davies 1 , Rebecca Holley 2 , Julie Webb 1 , Marianne Aznar 2 , Corinne Faivre-Finn 4,2 , David Woolf 4 , Margaret Harris 4 , Danya Abdulwahid 4 , Clara Chan 4 , Hamid Sheikh 4 , Kathryn Banfill 4,2 1 The Christie NHS Foundation Trust, Radiotherapy, Manchester, United Kingdom. 2 The University of Manchester, Division of Cancer Sciences, Manchester, United Kingdom. 3 The Christie NHS Foundation Trust, Radiotherapy Physics, Manchester, United Kingdom. 4 The Christie NHS Foundation Trust, Clinical Oncology, Manchester, United Kingdom

Purpose/Objective:

In the UK, trial activity is typically carried out by specialised research nurses. Here we present the results from the first therapeutic radiographer led prospective study at our centre, conducted by the radiotherapy clinical trials team. Our exemplar is the Remote Cardiac mOnitoring following lung RaDiotherapy (ReCoRd) study (IRAS: 289962), which facilitated the development of standardised procedures for radiographer led clinical trial delivery. Despite advances with modern radiotherapy, radiation-induced heart disease remains a common cause of morbidity and mortality in lung cancer patients treated with this modality. The clinical rationale for the ReCoRd study was to assess feasibility of cardiac monitoring using smartwatches in patients treated with curative-intent