ESTRO 2024 - Abstract Book

S5807

RTT - Education, training, advanced practice and role developments

ESTRO 2024

Late Urinary Toxicity and Treatment Modality

Late urinary toxicity was similar across all HDR-brachytherapy modalities (figure 2).

Lifestyle and Toxicity Incidence

Increased caffeine/alcohol intake and smoking did not coincide with greater incidence/severity of urinary, bowel or ED PROM scores. Data were obtained as discrete variables, thus correlation analysis was not performed.

No association/correlation was observed between BMI and IPSS scores (PEARSON:-0.11019, CORREL:-0.11019), however the small sample size is unlikely to provide a stable correlation.

Conclusion:

Patient-reported urinary and bowel toxicities were mild-moderate up to 36-months following HDR-brachytherapy as a monotherapy, salvage treatment or combined with EBRT. Reports of severe urinary symptoms were consistent with baseline LUTS. Most patients reported severe ED, however symptoms may be attributed to ongoing ADT.

These findings provide initial insight into long-term patient-reported outcomes following various HDR-brachytherapy methods, and provide novel data compared to previous clinician-reported toxicity studies. Continued PROMs use in