ESTRO 2024 - Abstract Book

S577

Clinical - Breast

ESTRO 2024

This study confirms previous findings that mDIBH with the ABC device significantly reduces cardiac dose. In our clinical practice, mDIBH with the ABC device is the preferred approach for cardiac sparing in LBC patients, demonstrating feasibility and safety in all our treatments. Only a small proportion (5%) of enrolled patients were ineligible due to device tolerability issues and severe hearing impairment.

Keywords: DIBH, left-sided breast cancer, ABC

References:

Darby SC, Ewertz M, McGale P, et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med. 2013 Mar 14;368(11):987-98. doi: 10.1056/NEJMoa1209825. PMID: 23484825.

Van den Bogaard VA, Ta BD, van der Schaaf A, et al. Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures. J Clin Oncol. 2017 Nov 10;35(32):3736. PMID: 28095159; PMCID: PMC5455600. Wang X, Pan T, Pinnix C,et al. Cardiac motion during deep-inspiration breath-hold: implications for breast cancer radiotherapy. Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):708-14. doi: 10.1016/j.ijrobp.2011.01.035. Epub 2011 Mar 26. PMID: 21444161; PMCID: PMC4158740.

Meattini I, Poortmans PM, Aznar MC, et al. Association of Breast Cancer Irradiation With Cardiac Toxic Effects: A Narrative Review. JAMA Oncol. 2021 Jun 1;7(6):924-932. doi: 10.1001/jamaoncol.2020.7468. PMID: 33662107.

Gaál S, Kahán Z, Paczona V, et al. Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility. Radiat Oncol. 2021 May 13;16(1):89. doi: 10.1186/s13014-021-01816-3. PMID: 33985547; PMCID: PMC8117634.

1745

Digital Poster

Does Radiotherapy Boost Technique to Positive Internal Mammary Lymph Node in Breast Cancer Matter?

Caglayan Selenge Beduk Esen, Yasin Ozyurek, Sezin Yuce Sari, Melis Gultekin, Gokhan Ozyigit, Ferah Yildiz

Hacettepe University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

Purpose/Objective:

Radiotherapy (RT) has a major role in locoregional control of internal mammary lymph node (IMLN)-positive breast cancer (BC), however, the optimal RT technique, field, and dose remain still controversial [1,2]. We aimed to evaluate the effect of RT boost techniques and doses to IMLNs on oncological outcomes and toxicity profile in clinically IMLN positive BC patients.