ESTRO 2024 - Abstract Book

S603

Clinical - Breast

ESTRO 2024

3. Puttanawarut C, Sirirutbunkajorn N, Tawong N, Jiarpinitnun C, Khachonkham S, Pattaranutaporn P, et al. Radiomic and dosiomic features for the prediction of radiation pneumonitis across esophageal cancer and lung cancer. Frontiers in Oncology. 2022;12:768152.

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5. Kraus KM, Oreshko M, Bernhardt D, Combs SE, Peeken JC. Dosiomics and radiomics to predict pneumonitis after thoracic stereotactic body radiotherapy and immune checkpoint inhibition. Frontiers in Oncology. 2023;13:1124592. 6. Lee SH, Han P, Hales RK, Voong KR, Noro K, Sugiyama S, et al. Multi-view radiomics and dosiomics analysis with machine learning for predicting acute-phase weight loss in lung cancer patients treated with radiotherapy. Physics in Medicine & Biology. 2020;65(19):195015.

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2045

Digital Poster

Tonsillitis toxicity after radiation therapy for breast cancer

Yevgeniy Ishkinin 1 , Radmila Akhunova 1 , Kairgeldi Datbayev 1 , Gulzhaina Kaldarbekova 1 , Botagoz Latypova 1 , Murat Omirzak 2 , Rauan Munalbayev 1 , Tatyana Antropova 1 , Ruslan Ibraev 1 , Rauan Raimbekov 1 , Nurnisa Makhmutova 1 , Saniya Ossikbayeva 3 1 Almaty oncology center, Almaty, Almaty, Kazakhstan. 2 Kazakh Institute of Oncology & Radiology, dosimetry, Almaty, Kazakhstan. 3 Kazakh Institute of Oncology & Radiology, science, Almaty, Kazakhstan

Purpose/Objective:

Despite modern treatment methods, radiation therapy (RT) for breast cancer entails a high probability of destructive changes in vascular endothelium and thyroid parenchyma, resulting in tonsillitis, which was detected on computed tomography (CT) images at the control study. It is necessary to analyze the conditions of tonsillitis appearance after breast cancer RT.

Material/Methods:

A prospective randomized controlled study of 137 breast cancer patients. Within the framework of the grant of the Ministry of Science and Higher Education of the Republic of Kazakhstan with an individual registration number AP13068657 «An innovative approach to the management of cancer patients in the COVID-19 pandemic». Of them, 68 patients (49.6%) underwent the moderate hypofractionated RT (HFRT), which on average included 16 sessions in