ESTRO 2024 - Abstract Book

S605

Clinical - Breast

ESTRO 2024

2058

Digital Poster

prospective correlation research on shoulder radiation dose and impairment in breast cancer patients

Pedram Fadavi 1 , Sepideh Soltani 1 , Manijeh Beigi 1 , Zahra Bagherpour 2 , Donya Davoodi 3 , Mahdie Jajroudi 4 , Maryam Garousi 1 1 Iran University of Medical Sciences, Radiation Oncology, Tehran, Iran, Islamic Republic of. 2 Shahid Beheshti University of Medical Sciences, Radiation Oncology, Tehran, Iran, Islamic Republic of. 3 Rofeideh Rehabilitation Hospital, Clinical Research Development Center, Tehran, Iran, Islamic Republic of. 4 Mashhad University of Medical Sciences, Pharmaceutical Research Center, Mashhad, Iran, Islamic Republic of

Purpose/Objective:

Breast cancer patients who undergo axillary lymph node dissection and regional nodal irradiation (RNI) frequently experience shoulder complications as significant long-term side effects [1, 2]. However, the relationship between radiotherapy and restricted shoulder mobility, decreased strength, and shoulder disability remains inadequately established [3, 5]. The primary objective of this study was to explore the correlation between radiation therapy dose in the shoulder area and the occurrence of shoulder complications in breast cancer patients. To assess shoulder function, we employed a comprehensive approach that encompassed measuring range of motion (ROM), evaluating muscle strength, and utilizing the quick disabilities of the arm, shoulder, and hand (qDASH) questionnaire score.

Material/Methods:

In this prospective study, we recruited 50 breast cancer patients who had been treated with adjuvant RNI with 3D conformal radiation therapy following surgery. Patients received conventional fractionation treatment with a total radiation dose of 5000 cGy in 25 fractions to the breast or chest wall area and regional nodes with or without a boost to the mastectomy scar or lumpectomy cavity. The delineated shoulder region extended from 2 cm above the upper boundary of the ipsilateral supraclavicular planning target volume (PTV) to the lowest slice of the supraclavicular PTV, encompassing relevant structures, including muscles, soft tissues, vasculature, and bones (excluding the vertebra) in the posterior neck, shoulder, and upper arm region (Figure-1).