ESTRO 2024 - Abstract Book

S780

Clinical - CNS

ESTRO 2024

Conclusion:

This single-center study emphasizes the importance of regular, close-follow-up examinations for the timely detection of new metastases, allowing for immediate therapeutic action. Our frequency analysis of repeated courses of radiosurgery reveals the recurrent nature of patient visits, illuminating the substantial clinical workload involved. These findings prompt a re-evaluation of current compensation structures for such therapies in Germany, considering the shift towards more frequent, precise treatments as opposed to a single extensive whole-brain radiotherapy session in the past. Additionally, our findings serve as a foundation for further multicentric studies, essential for corroborating these insights and informing more nuanced patient care strategies.

Keywords: Radiosurgery,Brain Metastases,Treatment Frequency

References:

[1] Kocher, Martin, et al. "Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study." Journal of Clinical Oncology 29.2 (2011): 134. [2] Brown, Paul D., et al. "Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC· 3): a multicentre, randomised, controlled, phase 3 trial." The Lancet Oncology 18.8 (2017): 1049-1060.

719

Digital Poster

De Ritis ratio in elderly glioblastoma patients treated with temozolomide-based chemoradiation

Jina Kim 1 , Hye In Lee 2,3 , In Ah Kim 2 , Joo Ho Lee 2 , Jaeho Cho 1 , Chan Woo Wee 1,2 , Hong In Yoon 1

1 Yonsei University College of Medicine, Radiation Oncology, Seoul, Korea, Republic of. 2 Seoul National University College of Medicine, Radiation Oncology, Seoul, Korea, Republic of. 3 Asan Medical Center, Radiation Oncology, Seoul, Korea, Republic of

Purpose/Objective:

Pretreatment laboratory parameters including De Ritis ratio and glucose level have been associated with prognosis in some types of solid tumors. Thus, we aimed to perform a comprehensive investigation on the prognostic value of pretreatment laboratory parameters in elderly glioblastoma patients treated with temozolomide-based chemoradiation.

Material/Methods: