ESTRO 2024 - Abstract Book

S882

Clinical - CNS

ESTRO 2024

Conclusion:

Conclusion: Although this systematic literature review shows a wide variation in HPA dysfunction after irradiation, the meta-analysis shows a prevalence for insufficiency on any axis of 63%. Therefore, it is of importance to gain more knowledge about the development HPA insufficiency over time, related to radiation dose to eventually determine the maximum tolerable dose to the HPA in radiotherapy treatment of brain, head and neck and skull base tumors. Taking quality of life aspects into account, endocrine follow-up on all axes is highly recommended in patients, irradiated for brain, head and neck and skull base tumors.

Keywords: Hypothalamo-pituitary axis, insufficiency

References:

[1] N. M. Appelman- Dijkstra et al., “Pituitary dysfunction in adult patients after cranial radiotherapy: systematic review and meta- analysis,” J Clin Endocrinol Metab, vol. 96, no. 8, Art. no. 8, Aug. 2011, doi: 10.1210/jc.2011 -0306.

2009

Digital Poster

REPEATED LINAC-BASED STEREOTACTIC RADIOTHERAPY AND RADIOSURGERY FOR MULTIPLE BRAIN METASTASES

Valerio Davì 1 , Fiorella Cristina Di Guglielmo 1 , Roberta Carbonara 1 , Ilaria Bonaparte 1 , Alessia Surgo 1 , Maria Paola Ciliberti 1 , Morena Caliandro 1 , Alba Fiorentino 2