ESTRO 2024 - Abstract Book

S893

Clinical - CNS

ESTRO 2024

Conclusion:

In this comprehensive treatment planning study of large intracranial targets treated with FSRS, GK plans resulted in similar or improved conformity and gradient indices compared to the other platforms, except for VMAT and ZAP-X, which resulted in an improved conformity and GI, respectively. However, GK required longer delivery times compared to the other platforms, excluding ZAP-X, which could be a consideration in clinical practice for technology selection. Ultimately, the choice of radiosurgery platform depends on specific treatment goals, patient characteristics, and clinical constraints, which underscore the imperative of a nuanced approach to technique selection.

Keywords: Fractionated SRS, brain metastases, platforms

References:

- Rogers, S., et al. (2022). Stereotactic radiosurgery and radiotherapy for resected brain metastases: current pattern of care in the Radiosurgery and Stereotactic Radiotherapy Working Group of the German Association for Radiation Oncology (DEGRO). Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 198(10), 919 – 925. https://doi.org/10.1007/s00066-022-01991-6

- Julie, D. A., et al. (2020). Stereotactic Radiosurgery Technology. Central Nervous System Metastases: Diagnosis and Treatment, 299-314.

- Dong, P., et al. (2016). Dosimetric characterization of hypofractionated Gamma Knife radiosurgery of large or complex brain tumors versus linear accelerator – based treatments. Journal of Neurosurgery JNS, 125(Supplement_1), 97-103. https://doi.org/10.3171/2016.7.GKS16881