ESTRO 2025 - Abstract Book

S1047

Clinical – Head & neck

ESTRO 2025

Conclusion: The addition of CT and PET image features to the updated clinical model enhanced iLN failure prediction. The addition of the shape feature Least-axis-length to the updated clinical model was particularly robust and demonstrated the best performance for iLN prediction.

Keywords: Pathological lymph nodes, Salvage treatment

References: [1]

Zhai TT, Langendijk JA, van Dijk L V., van der Schaaf A, Sommers L, Vemer-van den Hoek JGM, et al. Pre treatment radiomic features predict individual lymph node failure for head and neck cancer patients. Radiother Oncol 2020;146:58–65. https://doi.org/10.1016/j.radonc.2020.02.005. [2] Zhai TT, Wesseling F, Langendijk JA, Shi Z, Kalendralis P, van Dijk L V., et al. External validation of nodal failure prediction models including radiomics in head and neck cancer. Oral Oncol 2021;112:105083. https://doi.org/10.1016/j.oraloncology.2020.105083. [3] Cancer SE. Diagnostic Accuracy of Lymph Node Metastasis Depends 2013;54:670–6. https://doi.org/10.2967/jnumed.112.110304.

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Digital Poster Prognostication with lymphocyte counts and their kinetics during chemoradiotherapy for HPV-positive oropharyngeal carcinoma Alec Hughes 1 , Carlton Johnny 1 , Jie Su 2 , Enrique Sanz Garcia 3 , Anna Spreafico 3 , Lillian Siu 3 , Lawson Eng 3 , Scott Bratman 1 , B.C. John Cho 1 , Ezra Hahn 1 , Andrew Hope 1 , Ali Hosni 1 , John Kim 1 , Nauman Malik 1 , Brian O'Sullivan 1 , C. Jillian Tsai 1 , John Waldron 1 , John De Almeida 4 , Christopher Yao 4 , Li Tong 1 , Wei Xu 2 , Shao Hui Huang 1 , Andrew McPartlin 1 1 Department of Radiation Oncology, Princess Margaret Cancer Centre/University of Toronto, Toronto, Canada. 2 Department of Biostatistics, Princess Margaret Cancer Centre/University of Toronto, Toronto, Canada. 3 Department of Medical Oncology, Princess Margaret Cancer Centre/University of Toronto, Toronto, Canada. 4 Department of Otolaryngology-Head and Neck Surgery/Surgical Oncology, Princess Margaret Cancer Centre/University of Toronto, Toronto, Canada