ESTRO 2025 - Abstract Book

S1087

Clinical – Head & neck

ESTRO 2025

Results: Totally eight fractions of ART were executed for the four patients. The dose metric of OARs was lower than the original plan, but didn’t have significant difference. The dose metric of targets was better than the original plan. The V100 of GTVn and CTV2 had significant difference. The results were shown in Table 2.

Conclusion: The proposed automated ART decision-making system provided a unified standard for ART decision-making and without extra clinical resource usage. The prospective results shew that with the decision-making system, it improved the coverage of targets and reduced the dose of OARs.

Keywords: automated, adaptive radiotherapy, NPC

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Digital Poster Efficacy of administering pentoxifylline, tocopherol, with or without clodronate, to irradiated head and neck cancer patients with osteoradionecrosis Dustin Jan Cruz 1 , John Mohan Mathew 1 , Jolie Ringash 1 , Jie Su 2 , Wilfred Levin 1 , Scott Bratman 1 , John Cho 1 , Ezra Hahn 1 , Ali Hosni 1 , Andrew Hope 1 , John Kim 1 , Nauman Malik 1 , Andrew McPartlin 1 , Brian O'Sullivan 1 , C. Jillian Tsai 1 , John Waldron 1 , Anna Spreafico 3 , David Goldstein 4 , Melanie Woodside 1 , Samantha Parmelee 1 , Jennifer Y.Y. Kwan 1 , Erin Watson 5 , Wei Xu 2 , Shao Hui Huang 1 , Philip Wong 1 1 Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Canada. 2 Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, Canada. 3 Department of Medical Oncology, Princess Margaret Cancer Centre, Toronto, Canada. 4 Department of Otolaryngology-Head & Neck Surgery, Princess Margaret Cancer Centre, Toronto, Canada. 5 Department of Dentistry, University Health Network, Toronto, Canada