ESTRO 2025 - Abstract Book

S1210

Clinical – Lower GI

ESTRO 2025

Conclusion: Definitive CRT for SCCA spares patients morbidity of surgery; however, toxicity profile can’t be ignored: prevention and optimally treating adverse effects is imperative. Higher values of inflammatory markers can serve as predictors of higher recurrence rates and worse survival. Better knowledge of prognostic factors could help develop individualized therapies for patients as more reliable data from prospective studies could lead to the integration of these inexpensive and easy-to-derive tools into clinical practice.

Keywords: Anal Cancer, Radiation Therapy, Toxicity

References: 1. Clifford GM, et al. A meta-analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale. Int J Cancer. 2021 Jan 1;148(1):38-47. 2. Gondal TA, et al. Anal Cancer: The Past, Present and Future. Curr Oncol. 2023 Mar 11;30(3):3232-3250.