ESTRO 2025 - Abstract Book

S121

Invited Speaker

ESTRO 2025

FLASH-RT, novel beam monitoring and dosimetry technologies must be developed and new approaches studied. Indeed, currently used dosimeters for conventional radiotherapy, such as ionization chambers, are affected by large ion recombination effects at these extreme regimes. Therefore, the optimization of already established technologies as well as the investigation of new instrumentation for dosimetry is required. Alternative approaches are currently being investigated and their usage at UHDRs is under assessment. The challenges characterising dosimetry for FLASH radiotherapy vary considerably depending on the accelerator type and technique used to produce the relevant UHDR radiation environment. Different beam pulse structures can be used for the acceleration of the radiation beams, depending on the specific accelerator, and the related dose and dose-rate per pulse can affect the detector response. A reliable measurement also of the instantaneous dose rate, beyond an accurate measurement of the dose, is also relevant at these extreme regimes. The main challenges coming from the peculiar beam parameters characterising UHDR beams for FLASH RT will be reported in this talk. A status of the current technologies together with future perspectives will be discussed, including recent developments for established detectors and novel approaches currently under investigation.

4849

Speaker Abstracts Lung cancer radiotherapy: Pioneering trends and innovations for future practice Sarah Barrett Discipline of Radiation Therapy, Trinity College Dublin, Dublin, Ireland

Abstract:

Lung cancer radiation therapy (RT) is undergoing rapid evolution, driven by both clinical and technological advancements. This presentation will explore key innovations shaping current and future practice.

First, it will examine the changing demographic and clinical profiles of patients receiving radiotherapy for lung cancer and highlight the broad spectrum of indications of RT in lung cancer.

Next, the talk will consider the recent advancements in image-guided radiotherapy (IGRT), particularly the role of enhanced on-treatment cone-beam computed tomography (CBCT) and MR guided RT. These technical developments facilitate not only improved geometric verification but may also enable more widespread integration of adaptive radiotherapy (ART) in clinical practice. The critical considerations of who , when , and how to implement ART in lung cancer will be addressed. Artificial intelligence (AI) is increasingly embedded across the radiotherapy pathway, and its expanding role in lung cancer treatment will be illustrated through key examples. These technical innovations could contribute to a more individualized approach to patient care, and research on personalised RT for lung cancer will be presented. Finally, the evolving role of radiation therapists (RTTs) will be discussed, particularly in the context of increased imaging and adaptive workflows, underscoring their critical contribution to the delivery of high-quality lung cancer radiotherapy.