ESTRO 2025 - Abstract Book

S1384

Clinical - Lung

ESTRO 2025

2. Two months later. 3. Five months later.

Results: Emotional Reactions to Diagnosis Announcement Patients exhibited a wide range of intense emotional responses: • 95% experienced emotional shock. • 88% reported severe anxiety. • 84% felt sadness or depression. • 79% feared death. • 77% expressed concerns about stigma, especially related to smoking or visible side effects like weight loss and hair loss. • 82% faced heightened stress due to financial concerns. Progression of Anxiety and Depression • Anxiety : o 93% exhibited high levels of anxiety at diagnosis. o This decreased to 68% after two months and 45% after five months. • Depression : o 87% experienced significant depressive symptoms at diagnosis. o This figure dropped to 61% after two months and 38% after five months. Quality of Life • 92% of patients reported a significant decline in their quality of life immediately after diagnosis. • Two months later, 54% experienced slight to moderate improvement. • Five months post-diagnosis, 67% reported moderate improvements in quality of life. Access to Psychological Support • 52% of patients sought professional psychological counseling to help cope with stress and emotional challenges. Conclusion: This study reveals the profound psychological impact of a lung cancer diagnosis, characterized by high levels of anxiety, depression, and reduced quality of life. While improvements were noted over time, these findings underscore the critical need for long-term psychological support and follow-up care to promote the well-being of lung cancer patients throughout their treatment journey.

Keywords: Lung cancer; Psychological impact; Quality of life

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Poster Discussion Radical Dose Re-Irradiation for Relapsed Non-Small Cell Lung Cancer; Real World Data on Impact of Guidelines and Survival Outcomes Jin Tee 1 , Cathryn Crockett 1 , Karen Tumelty 1 , Jolyne O'Hare 1 , Linda Young 1 , Jonathan McAleese 1,2 1 Northern Ireland Cancer Centre, Belfast Health & Social Care Trust, Belfast, United Kingdom. 2 School of Medicine, Dentistry & Biomedical Sciences, Queens University Belfast, Belfast, United Kingdom Purpose/Objective: Early detection and treatment of recurrences in order to salvage cure is an advantage of close follow-up for radically treated patients with NSCLC. Previous studies 1,2 detected isolated intrathoracic relapse (ITR) in 12-15% and second primary (SP) in 10-11% of patients. Patients with SP received SCT in 40-58%. However, Salvage Cure Treatment (SCT) for an ITR was much lower; 24% after initial surgery and only 3% after initial radical radiotherapy (RR). At our centre,