ESTRO 2025 - Abstract Book

S1500

Clinical – Mixed sites & palliation

ESTRO 2025

Material/Methods: The APP script was developed to generate a VMAT plan conformal to the PTV, but without OAR optimisation. Following delineation of the PTV, the RO ran the script from the Eclipse Treatment Planning workspace to generate a VMAT “AutoPlan” which was available for immediate plan approval. Initial feasibility assessment had been performed by running the script retrospectively on 35 patients who had completed 40 courses of palliative radiotherapy. The current study used the APP script to prospectively generate treatment plans for patients requiring palliative radiotherapy. Suitable patients were: ECOG 0-3, who would otherwise have been treated with a Single Field, Parallel Opposed Pair, or 3D-Conformal technique. The standard VMAT planning care path required input of the RO at two time points: (1) Contouring volumes (2) Approval of the plan and prescription. These two steps were combined into a single step, with total time required <10min. Radiation therapists and Physicists checked the plan quality prior to treatment delivery. Results: Twenty patients treated by five ROs were included. Dose prescribed was 8Gy-30Gy in 1-8 fractions. Sites treated included bones, brain, lung, and pelvic viscera. Two patients required plan modification. Case 1 was a patient receiving radiation to the abdomen, and the RO preferred a lower kidney dose and standard optimised VMAT was used. Case 2 was a patient receiving palliative radiation to the prostate, and an established prostate Rapidplan model was used instead. All other plans were approved with no changes. The average time from CT simulation to plan approval was 2.10 days (0-7 days). The average time taken to run the script was 3.57 minutes (2.11 – 8.50 minutes). Conclusion: An automated palliative planning (APP) script to generate rapid VMAT plans was an effective tool in conjunction with streamlined work processes to facilitate timely access to palliative VMAT radiotherapy. Digital Poster Efficacy and tolerability of single fraction radiotherapy for spinal bone metastases in a low-middle-income country setting: a prospective study. Altaf Hossain 1 , Erika Galietta 2,3 , Alessio Giuseppe Morganti 2,3 , AFM Kamal Uddin 4 , Nowshin Taslima Hossain 5 , Tasneem Hossain 6 , Qazi Mushtaq Hussain 7 , Md Rahmatullah Bhuiyan 8 1 Radiotherapy and Oncology, Khulna Medical College Hospital, Khulna, Bangladesh. 2 Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. 3 Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum – Bologna University, Bologna, Italy. 4 Radiation Oncology, National Institute of ENT, Dhaka, Bangladesh. 5 Radiation Oncology, Ahsania Mission cancer & General Hospital, Dhaka, Bangladesh. 6 Radiation Oncology, National Institute of Cancer Research & Hospital, Dhaka, Bangladesh. 7 Clinical and Radiation Oncology, Labaid Cancer and Superspeciality Centre, Dhaka, Bangladesh. 8 250, Bedded General Hospital, Brahmanbaria, Bangladesh Purpose/Objective: This study aimed to evaluate the symptomatic efficacy and tolerability of three different radiotherapy regimens for patients with vertebral metastases in a low-middle-income country setting, focusing specifically on the effectiveness of single fraction radiotherapy. Keywords: Automated, Tool, VMAT 1909