ESTRO 2025 - Abstract Book

S1502

Clinical – Mixed sites & palliation

ESTRO 2025

lung (34%), head and neck (14%), breast (10%) and genitourinary (10%). Intent was curative in 46% and palliative in 54%. The average time from computed tomography scan planning to the start of radiotherapy was 16 days. The mean treatment completion rate was 55%. Overall, medical complications were the main reason for treatment discontinuation, affecting 104 patients (46%). More than half of these complications were attributed to non oncological conditions (infection, ictus, etc.) while the rest were due to oncological causes (progression disease, deterioration, etc.). Demise was the second most common cause, affecting 95 patients (42%) primarily due to cancer-related factors. Other reasons included patient's decision (8%), changes in treatment indication (3%) and technical difficulties (1%). Focusing on the palliative scenario, radiotherapy discontinuation is primarily due to deaths (60%) followed by medical complications (34%).

Conclusion: Incidence of treatment interruptions reported is low. Nevertheless, it's crucial to continue using tools to assess risks, optimize hospital resources and avoid overexposure to treatment — particularly for palliative patients. Also ensuring