ESTRO 2025 - Abstract Book

S1704

Clinical - Sarcoma & skin cancer & malignant melanoma

ESTRO 2025

first 2 years, and six monthly after that till year five. Treatment response was assessed at 3 months post-completion of treatment with clinical evaluation, MR scan and PETCT.

Results: Three (3) out of four (4) patients achieved complete clinical response at 3 months. One patient who did not achieve a complete response was successfully salvaged with surgical-wide local resection.

Fig 1a

Fig 1b

Fig 1a Before and Fig 1b after radiotherapy medical photos. Fig 1b shows Only residue scar after treatment.

Conclusion: Given the risk of surgery in this population and the low risk of metastasis, perianal BCC should be treated with radiotherapy, and surgical resection should be reserved for residual or recurrent disease.

Keywords: perianal basal cell carcinoma, anal malignancy,

References: [1] G. E. Gibson and I. Ahmed, ‘Perianal and genital basal cell carcinoma: A clinicopathologic review of 51 cases’, J. Am. Acad. Dermatol., vol. 45, no. 1, pp. 68–71, Jul. 2001. [2] T. Y. Tsai et al., ‘Perianal Basal Cell Carcinoma-A Systematic Review and Meta-Analysis of Real-World Data’, Diagnostics (Basel, Switzerland), vol. 13, no. 9, May 2023.