ESTRO 2025 - Abstract Book

S1909

Clinical - Urology

ESTRO 2025

Conclusion: By reducing high doses to the rectum, SpaceOAR enables higher doses to be prescribed to the DILs located close to the rectum. Moreover, cone beam CT with 6 degrees of freedom couch used for patient setup and triggered kV imaging for tracking intraprostatic motion can reliably monitor the prostate position, ensuring safe treatment delivery 1 . Consistent with published evidence, these have the potential to improve the patient's therapeutic ratio 2 .

Keywords: SpaceOAR, DIL Boost

References: 1.

Goodman, C. D., Fakir, H., Paulter, S., Chin, J., & Bauman, G. S. (2020). Dosimetric Evaluation of PSMA PET Delineated Dominant Intraprostatic Lesion Simultaneous Infield Boosts. Advances in Radiation Oncology, 5 , 212-220. 2. Kerkmeijer, L. G., Groen, V. H., Pos, F. J., Haustermans, K., Monninkhof, E. M., Smeenk, R. J., . . . Heide, U. v. (2021, Mar 1). Focal Boost to the Intraprostatic Tumour in External Beam Radiotherapy for Patients with Localized Prostate Cancer: Results from the FLAME Randomized Phase III Trial. Journal of Clinical Oncology, 39 (7), 797-796.