ESTRO 2025 - Abstract Book

S1924

Clinical - Urology

ESTRO 2025

Conclusion: The "4 Influencers" workflow significantly reduces target corrections and thus human intervention, supporting a more near-automated process. Further improvements should focus on safely reducing influencer adjustments to optimize treatment time and keep adaptive target volumes consistent with initial volumes.

Keywords: online adaptive radiotherapy, prostate cancer

References: 1. Sibolt P, Andersson LM, Calmels L, et al.: Clinical implementation of artificial intelligence-driven cone-beam computed tomography-guided online adaptive radiotherapy in the pelvic region. Physics and imaging in radiation oncology. 2021; 17: 1-7.

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Digital Poster Are evidence-based guidelines translating into clinical practice: a national study on the use of radiotherapy to the prostate for low burden mHSPC Joanna Dodkins 1 , Adrian Cook 2 , Thomas E Cowling 1 , Noel Clarke 3 , Alison Tree 4 , Jan van der Meulen 1 , Ajay Aggarwal 1 1 HSRP, London School of Hygiene and Tropical Medicine, London, United Kingdom. 2 Clinical Effectiveness Unit, Royal College of Surgeons of England, London, United Kingdom. 3 Urology, The Christie and Salford Royal NHS Trusts, Manchester, United Kingdom. 4 Clinical Oncology, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom Purpose/Objective: International guidelines recommend radiotherapy to the prostate for patients with low-burden metastatic hormone-sensitive prostate cancer (mHSPC) based on RCT evidence. This study aimed to assess the utilisation of radiotherapy to the prostate in potentially eligible patients with mHSPC in the English National Health Service (NHS) and to investigate the patient, tumour and hospital level factors associated with variation in treatment.