ESTRO 2025 - Abstract Book

S2247

Interdisciplinary – Global health

ESTRO 2025

which were distributed to experts from each NS. We received 48 responses from various NSs, resulting in a consolidated list of 65 QIs. In the second Delphi round, with feedback due by December 20, 2024, we aim to refine this list to a minimal set of 30-40 key QIs. Conclusion: The abundance of information internationally on QIs in radiotherapy is encouraging but can be overwhelming for departments willing to implement them for quality improvement and benchmarking. A consensus on a minimal, general, non-site-specific set of QIs relevant to the European context is needed. This standardized set will simplify self-auditing within centers and allow for multicentric data collection, aiding European-level benchmarking. Such harmonization is crucial for assessing and enhancing radiotherapy quality across Europe, ensuring consistent and high-quality patient care.

Keywords: quality assurance, quality indicators

3642

Digital Poster Efficacy of single-versus multi-fraction radiotherapy for bone metastases pain management in developing countries: a meta-analysis. Erika Galietta 1,2 , Von KAGANDA BOMBOKA 1 , Costanza Maria Donati 1,2 , Letizia Cavallini 1,2 , Francesco Cellini 3,4 , Milly Buwenge 1 , Tigeneh WONDEMAGEGNEHU 5 , Biniyam Tefera DERESSA 6 , Kamal A.F.M. Uddin 7 , Mostafa A Sumon 8 , Maria Vadala' 9 , Rebecca Sassi 10 , Alberto Bazzocchi 10 , Martijn Boomsma 11 , Francesca De Felice 12 , Simone Ferdinandus 13,14 , Silvia Cammelli 1,2 , Alessio Giuseppe Morganti 2,1 1 Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - Bologna University, Bologna, Italy. 2 Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. 3 Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy. 4 Istituto di Radiologia, Cattolica del Sacro Cuore, Rome, Italy. 5 Radiotherapy Department, Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. 6 Radiation Oncology, Adama Hospital Medical College, Adama, Ethiopia. 7 Department of Radiation Oncology, United Hospital Limited, Dhaka, Bangladesh. 8 Radiation Oncology, Kurmitola General Hospital, Dhaka, Bangladesh. 9 Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bollogna, Italy. 10 Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. 11 Department of Radiology, Isala Hospital, Zwolle, Netherlands. 12 Department of Radiological, Oncological and Pathological Sciences, ,“Sapienza” University of Rome, Rome, Italy. 13 Department of Radiation Oncology, Cyberknife and Radiotherapy, Faculty of Medicine and University Hospital Cologne, Cologne, Germany. 14 Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany Purpose/Objective: This study aims to assess the efficacy of palliative radiotherapy (RT) for managing pain in patients with bone metastases (BM), with a particular focus on single-fractionation versus multi-fractionation RT. Despite existing evidence from high-income countries suggesting comparable effectiveness between these two approaches, there is a notable scarcity of data pertaining to low/middle-income countries (LMICs). This gap is significant, given the resource constraints in LMICs that potentially prolong diagnostic and treatment processes and amplify patient load. Consequently, this research undertakes a meta-analysis to evaluate the relative effectiveness of single versus multiple fractionation of palliative RT for BM in LMICs. Material/Methods: An extensive literature review was conducted independently by two researchers across PubMed, Cochrane, and Scopus databases. From the initial 333 records screened, 4 randomized trials involving 282 patients from Iran, India, and Egypt were included in this meta-analysis.