ESTRO 2025 - Abstract Book

S228

Brachytherapy - Gynaecology

ESTRO 2025

Table 1: clinical studies on the use of external beam radiotherapy in place of brachytherapy in endometrial cancer

Conclusion: This review highlights that, while modern EBRT techniques like IMRT and VMAT are feasible alternatives to BRT for postoperative vaginal cuff irradiation, current evidence does not support their superiority over BRT, particularly in definitive radiotherapy settings. BRT remains a highly effective treatment modality with well-established benefits in EC management. Future research should focus on more robust comparisons between EBRT and BRT, considering not only local control and toxicity but also the psychological impact and quality of life, especially in low-resource settings where access to BRT may be limited.

Keywords: endometrial cancer, systematic review, SBRT